A 78-year-old man with hemorrhagic transformation of a 17cm pseudocyst was hemodynamically unstable requiring splenic artery embolization. He developed gastric outlet obstruction due to the pseudocyst, which was then drained under EUS guidance by creating a cystgastrostomy, flushing the cavity with hydrogen peroxide and placement of a through-the-scope, covered esophageal metal stent (18mm x 60mm) across the cystgastrostomy. A total of 2.4L of blood was drained during the procedure. The patient experienced a rapid resolution of symptoms post-procedure. At 4 week imaging, the pseudocyst had completely resolved after a single procedure. The stent was easily removed with a snare at follow-up endoscopy.
We have demonstrated a novel technique which facilitates safe and rapid resolution of a giant pseudocyst with large volume solid debris (blood clots) without the need for repeated endoscopic procedures, debridement or external drainage. Hydrogen peroxide facilitated dissolution of the blood clots. The wide bore stent allowed passage of debris from the pseudocyst cavity without becoming clogged. The wide caliber covered metal stent also ensured complete seal of the cystgastrostomy tract, preventing complications of leaks and perforation.